
An experimental study of a new weight loss drug known as Tesofesine, has been shown to be twice as effective as other weight loss medications on the market. Tesofesine, which works as an appetite suppressant, showed that in a study of 161 participants, the average weight loss over a 6 month study was between 3 – 13kg, depending on the dosage of the drug.
Funded by Danish biopharmaceutical company Neurosearch in the hope of using testofesine as a weight loss drug, studies were carried out at University of Copenhagen. Researcher and university MD, Arne Astrup said “Normally the drugs now on the market give you at best a weight loss of 5 kilograms (11 pounds) with diet and exercise. In this study we doubled that weight loss."
Tesofensine, which has previously been studied to treat Alzheimer’s and Parkinson’s disease, showed limited efficacy in treatment for these diseases, but significant weight loss in trial participants who were obese. It works by affecting three different appetite regulatory centres of the brain, in the form of neurotransmitters noradrenaline, dopamine and serotonin.

On the Lemon Detox Diet, dieters are encouraged to have a large glass of water each day with 1 teaspoon of salt, which helps stimulate bowl movements. This can also be substituted with Senna tea (1 teaspoon) in the evening if the salt water drink can not be stomached.
In addition, the actual syrup used for the Lemon Detox Diet is enriched with vitamins. As such if you follow a home recipe it is recommended you have a multi-vitamin or mega multi-vitamin each day.
To follow
the diet you are meant to have between 6-10 glasses of the detox drink each day
and nothing else (except for the morning salt drink or herbal tea). The detox process is meant to be followed for between
3 – 7 days.

While the low carbohydrate diet showed faster results than the big breakfast diet, over the 8 month period the big breakfast group lost significantly more weight in the long term. The big breakfast diet group had lost on average 18 kg while the low carbohydrate group had lost 12.8kg by four months, but regained 8.2 kg by the eight month mark.
So the saying ‘breakfast like a king, lunch like a prince and dine like a pauper’ may actually hold true for effective long term weight loss.


Firstly you need to know how many calories your body burns naturally, known as your basal metabolic rate (BMR). This is the energy required for your basic body functions and includes beating
of the heart, breathing, and the maintenance of body temperature. It is
a function of your age, weight, height, gender and exercise habits. Take our diet profile to work out your BMR.
You can then use our food to work out the calories in the food you eat. You simply need to search for the food and enter in the quantity and it will provide the calories and all nutritional information. A good idea is to start with a standard day and work out how many calories you would normally eat. The results also show how much exercise you would have to do to burn it off!

When people want to lose weight they often want to do it fast. This is definitely one of the biggest challenges with weight loss as there is a delay between hard work and achievement. There are a number of reasons that contribute to making fast weight loss difficult. Primarily this is due to the fact that when you have a large calorie deficit (burn more calories than you eat) your body goes into starvation mode. Lack of fluids is another major reason for unsustainable fast weight loss. Our body is made up of 70 - 75% water, so levels of only 2% dehydration would lead to a weight loss of nearly 2kg. This weight is put straight back on when fluids are put back into the body. In addition, hunger becomes a real distraction for fast weight loss as your body is crying out for calories to fulfill even the most basic bodily needs.
So how fast can you actually lose weight?
Let's look at Mary, who is 32 years old and weighs 80kg. By looking at a few extremes we can see how quickly weight loss is actually possible. If May ate absolutely nothing for a week, she would have eaten 0 calories against around 14,000 calories burnt. Now it takes around 7,600 calories to burn 1kg of fat so this would equate to weight loss of around 1.8kg.


